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Pulmonary Bioinformatics: Mechanism, Biomarkers and Therapies

Edited by: Dr Galina Bogatkevich, Prof Richard Gronostajski, Prof Yoshinori Marunaka, Prof Xiangdong Wang, Dr Yan Xu

Collection published: 20 January 2011

Last updated: 20 December 2011

Pulmonary diseases are one of the most common causes responsible for high mortality and morbidity, including asthma, chronic obstructive pulmonary disease, restrictive lung diseases, airway infections, lung cancer, pleural cavity diseases, and pulmonary vascular diseases. Recent advances in bioinformatics have introduced new technologies to study the mechanisms, biomarkers and therapies for pulmonary diseases. Knowledge and understanding of these conditions have led to the development of animal models, successful therapies, and novel tools to characterize these clinical conditions and provide better care to patients.

This series aims to publish original research articles and review articles that will stimulate the continuing efforts to understand the molecular pathology underlying pulmonary diseases, the development of strategies to treat these conditions, and the evaluation of outcomes. The series is still accepting submissions; the call for papers provides more information.


Review   Open Access

Significance of bioinformatics in research of chronic obstructive pulmonary disease

Hong Chen, Xiangdong Wang Journal of Clinical Bioinformatics 2011, 1:35 (20 December 2011)

Abstract | Full text | PDF | PubMed

Research   Open Access

Peripheral blood gene expression profiles in COPD subjects

Soumyaroop Bhattacharya, Shivraj Tyagi, Sorachai Srisuma, Dawn L DeMeo, Steven D Shapiro, Raphael Bueno, Edwin K Silverman, John J Reilly, Thomas J Mariani Journal of Clinical Bioinformatics 2011, 1:12 (24 April 2011)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

A filter-based feature selection approach for identifying potential biomarkers for lung cancer

In-Hee Lee, Gerald H Lushington, Mahesh Visvanathan Journal of Clinical Bioinformatics 2011, 1:11 (21 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Database   Open Access

Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database

Mosmi Surati, Matthew Robinson, Suvobroto Nandi, Leonardo Faoro, Carley Demchuk, Cleo E Rolle, Rajani Kanteti, Benjamin D Ferguson, Rifat Hasina, Tara C Gangadhar, April K Salama, Qudsia Arif, Colin Kirchner, Eneida Mendonca, Nicholas Campbell, Suwicha Limvorasak, Victoria Villaflor, Thomas A Hensing, Thomas Krausz, Everett E Vokes, Aliya N Husain, Mark K Ferguson, Theodore G Karrison, Ravi Salgia Journal of Clinical Bioinformatics 2011, 1:8 (28 February 2011)

Abstract | Full text | PDF

Review   Open Access

RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers

Eri Kawata, Eishi Ashihara, Taira Maekawa Journal of Clinical Bioinformatics 2011, 1:6 (20 January 2011)

Abstract | Full text | PDF


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